A stem-cell-derived human embryo model showing yellow cells (yolk sac), blue cells (embryo) and pink cells (placenta)
Researchers at the Weizmann Institute of Science, led by Prof. Jacob Hanna, have successfully grown an embryo model resembling an early human embryo, without using sperm, or eggs, or a womb.
Developed using lab-cultured stem cells, the human embryo grew outside the womb up to day 14. However, it cannot be implanted into a real human womb.
The model exhibited remarkable similarities to a natural embryo, featuring key structures like the epiblast, trophoblast, hypoblast cells, and extraembryonic mesoderm cells. It even released hormones turning a pregnancy test positive.
However
While these models offer invaluable insights, ethical and regulatory considerations persist regarding their treatment and extension beyond the 14-day limit. Researchers are hopeful that embryo models will help improve IVF success.